10 years before the present, Dr. Genome was one of Dr. Kogami's assistants who helped him plan and execute the Hanoi Project. Together with Kogami, Aso, and Kyoko Taki, he helped create the Ignis - six AI with free will based on the Lost Incident victims and the Duel Monsters attributes. When SOL Technologies infected Dr. Kogami with a computer virus to cover up the Hanoi Project, he helped recreate his consciousness inside the network, faithfully serving as a Knight of Hanoi ever since.
Genome plays a "Helixx" Deck. His strategy involves summoning high level monsters without tributing and using them for Link Summons. Some of his cards involve preventing damage.