Des Frog, known as Death Frog in the Japanese version, is a character version of the card, "Des Frog".
In Yu-Gi-Oh! GX, the Des Frogs were believed to be Duel Monster spirits seen by Princess Rose (manifested as three "princes" named Jeffrey, Roosevelt and Percival in the English dub), but others do not believe her. Jaden, however, notices the spirit of a frog prince watching over her after their duel.
Des Frog appears in the video games, Yu-Gi-Oh! Ultimate Masters: World Championship 2006 and Yu-Gi-Oh! World Championship 2007. In World Championship 2007, he appears as a Level Two Theme Duelist and he challenges the player to make him run out of cards in his deck. By beating him, the player gets closer to unlocking Level Three Theme Duelists and a new booster pack.