Curse of Vampire appears in the video game, Yu-Gi-Oh! World Championship 2008. He first appears bullying Gigobyte and will stop, if the player beats him in a Duel. By beating him the first time, he can be unlocked as a single duel opponent and by beating him ten times, he can be unlocked as a tag partner.
In World Championship 2008, Curse of Vampire uses a Zombie Deck titled "Eternal Spirit" and "The Curse".