• This card has been reprinted twenty-eight times, more than any other card.
  • Many players joke that "MST negates", due to beginners often mistakenly believing that destroying a card negates its effect, and thus that "Mystical Space Typhoon" can be chained to an activated Spell or Trap Card to negate its effect.
  • This is one of only two cards to have appeared in all Yu-Gi-Oh! movies, along with "Polymerization".