This card is based around the stock character The Mad Scientist in fiction. Many believe this character archetype sprouted from Mary Shelley's character Dr. Victor Frankenstein, from her novel Frankenstein. A monster card based on Frankenstein's monster, "Cyber-Stein", has a very similar effect, paying life Points to Special SummonFusion Monsters.
In a similar vein, this card's Japanese name contains a pun: "Madō" translates into "magical", but can also be interpreted as a transliteration of "mad"; thus, "Magical/Mad Scientist".
As seen in "Success Probability 0%", he seems to be friends with "Kozaky".
The background of this card slightly resembles the processing chambers from the Guyver franchise.
In card artworks, "Magical Scientist" is shown to have purple hair. However, his hair is brown in the anime.