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  • Use "DNA Surgery" to activate Oxygeddon's effect easier.
  • Use "Nature's Reflection" or "Barrel Behind the Door" to inflict another damage to your opponent's Life Points.
    • "Barrel Behind the Door" can works while the owner used this card's effect while "Nature's Reflection" work when the opponent used this card's effect.
  • If facing a Pyro-type strong monster (such as "Goka, the Pyre of Malice"), you may simply activate "Chthonian Blast" in order to destroy the monster that has destroyed this card, also taking an extra Effect Damage.

Traditional Format

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