Use this card with "Quillbolt Hedgehog" so that you can have a card that constantly Summons itself when you have a Tuner on the field. By using three copies, Summoning high-Level Synchro Monsters will not be very hard.
The Quillbolt Loop uses the effect of "Quillbolt" to revive itself while this card is active as well as a 'Tribute for damage' effect such as "Cannon Soldier". This idea requires 1 Tuner on the field, "Quillbolt" on the field or in the Graveyard, the 'Tribute for damage card' active, and this card active. By Tributing "Quillbolt" for the 'Tribute for damage card's effect, "Quillbolt" will return to the Graveyard instead of being banished due to this card. Then the Tuner allows the return of "Quillbolt". Rinse and repeat.
You can also use "Plaguespreader Zombie" with this combo for the cost of returning cards to the Deck to continuously Summon Level 8 or lower Synchro Monsters to swarm the field as "Plaguespreader" won't be banished due to "Imperial Iron Wall".
Using this card with "Exodia Necross" will keep all the pieces of "Exodia" in the Graveyard from being banished (and thus keeping "Exodia Necross" alive).
This card's effect only works one way: It only prevents cards from being banished; players are free to use effects to return cards that were already banished. Thus, you can activate "Return from the Different Dimension" to bring back your banished monsters and not have to worry about losing them at the end of the turn.
Use this card with "Mirage Knight" to have a powerful monster that basically can't be destroyed by battle.
You can chain "Allure of Darkness" with this card, if you do, you won't have to banish the DARK monster in your hand. After drawing two cards, you will need to reveal 1 DARK monster from your hand, and the revealed DARK monster remains in your hand.
This card is ideal for canceling out the effect of "Firewall".
This card works well in a Deck that revolves around "Stardust Dragon/Assault Mode" after using the effect of "Stardust Dragon/Assault Mode".
This is an essential side-Deck card for any Deck, which revolves around a key monster and the Graveyard (eg. "Machina Fortress"), or else "Karma Cut" will eat you alive. In the case of "Machina Fortress", this card can also stop "System Down".
Use this card in a "Paleozoic" deck to keep the archetype's Trap Cards from banishing themselves when they leave the field while they are treated as Normal Monsters, so you can Special Summon them from the Graveyard again later on.