- This card can be searched by "Dogu", "Single Purchase", "Heraldic Beast Leo", "Dragunity Corsesca", "Dragunity Knight - Gae Dearg", "Ninjitsu Art of Super-Transformation", "Dragonic Guard", "Draconnection", "Hieratic Dragon King of Atum", "Tempest, Dragon Ruler of Storms", "Vampire Dragon", "Kujakujaku", "Divine Wind of Mist Valley", "Summoner Monk", "Soul Rope" and "Resonator Engine".
- This card combos well with "Heraldic Beast Leo" in different ways; as you can get a Heraldic Beast monster from your deck when discarding "Leo" for the Special Summon of this card.
- After getting another Heraldic Beast monster, you can discard the added monster via this card's effect to increase its ATK, then use "Advanced Heraldry Art" to Special Summon "Leo" and the discarded monster for a quick Rank 4 Xyz Summon– all without using one's Normal Summon.
- One could Normal Summon the added Heraldic Beast monster, and perform a second 2-material Rank 4 Xyz summon between it and "Amphisbaena".
- If you also have "Heraldic Beast Eale" in your hand (or if you have another Heraldic Beast monster in your hand, you can add "Eale" via "Leo's" effect, instead), you can Special Summon it after Normal Summoning the other Heraldic Beast monster from your hand. Now, you have 3 Heraldic Beast monsters to work with for an even wider variety of summons.
- If you Special Summoned this card via its own effect, you can use it with a Tuner monster to Synchro Summon an appropriate Synchro Monster.
- And if you have "Advanced Heraldry Art" in your hands, just Special Summon both Heraldic Beast monsters for a quick Rank 4 Xyz Summon.
- A good combo with "Advanced Heraldry Art", is to discard 2 Heraldic Beast monsters with the same Attribute or Type for "Amphisbaena's" Special Summon and its effect, to Xyz Summon a Rank 4 Xyz monster that requires 2 monsters of that Attribute or Type.
- This card can be searched by "Witch of the Black Forest".