This card can be very effective against Lightsworn Decks, because its effect can stall or even prevent your opponent from summoning "Judgment Dragon".
This card's ATK boosting effect can be used as many times as you want, as long as your opponent has monsters in their Graveyard to be banished and you have one equip spell card equipped to "Guardian Eatos" to send to the Graveyard.
Equip this card with "Sword of Deep-Seated" or other card that return on top of your Deck when that card is sent to the Graveyard and reuse its effect again.
Alternatively, you can use "Spirit Burner", which remains in the graveyard until your next Draw Phase and gives you the option of retrieving it instead of conducting your normal draw. "Spirit Burner's" effect can also be used whenever it is in the Graveyard during the Draw Phase, so it can be reused even after your first "Eatos" is destroyed.
Equip this card with "Power Pickaxe", so you'll be able to banish another monster.
Use "Collected Power" to draw all Equip Spells on the field to "Guardian Eatos", and use its effect multiple times.
Use this card in a NightGusto deck for emergency purpose.
This card works well with "Gilford the Legend", as summoning the latter allows you to equip a large number of equip spells to "Eatos", who can then activate her effect more time. This can even be used to recycle previously tributed equip spells.
Note that you cannot directly use "Gilford's" effect on "Eatos". You will have to use "DNA Surgery", or "Collected Power".
In an all DARK deck, you can summon "Prometheus, King of the Shadows" and activate its effect to banish all DARK monsters in your graveyard. Afterwords, you can Special Summon "Guardian Eatos" from your hand. This combo will give you two very powerful monsters in one turn.
This card is a strong follow-up after banishing DARK monsters from your graveyard for the effect of "Dark Armed Dragon".
This card has high synergy in "Dark Simorgh" Decks you can banish extra copies of "Eatoses" in your graveyard for its effect and to set up for an "Eatos" summoning.
This card is perfect to summon on your first turn, as it is unlikely that you would have any monsters in your Graveyard.