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  • "Dark Snake Syndrome" works well with "Des Wombat", as "Des Wombat" will prevent any effect damage you take. This results in your opponent taking all the damage from "Dark Snake Syndrome".
  • This card will win you the duel after 6 turns, assuming you can protect your life points.
  • This card works well with "Black-Winged Dragon". Burning your opponent while you take no damage and "Black-Winged Dragon" gains counters for its effect.
  • You can combine "Dark Snake Syndrome's" effect with cards such as "Gem Flash Energy" or "Dark Room of Nightmare"; thus whilst taking damage, your opponent will sustain more damage than you.

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