• For an OTK, set "Micro Ray" on the field, then Fusion Summon this card. Use "Micro Ray" to lower your opponent's monster's DEF to 0. Play "Limiter Removal" if "Power Bond" isn't played, and do a full 8000 points of damage.
    • "Power Bond" can also be used to Fusion Summon this card and play "Limiter Removal" to have a monster with 16,000 ATK for another OTK.
    • All of the above card can be activated during The Damage Step. Only Counter Trap or ATK/DEF changer can be activated there.
  • "Mystik Wok" works well with "Cyber End Dragon", especially if it has had its ATK increased by "Power Bond" and/or "Limiter Removal".
  • Use "Power Bond" to Summon this card, and then Tribute "Cyber Kirin" so that no damage is taken.
  • If your Fusion Materials are in the Graveyard, use "Polymerization" or "Power Bond" and "Cybernetic Fusion Support" together to easily Summon this card. (Be careful if "Power Bond" is used, as its final effect must be cautious.)
  • Normal Summon "Cyber Dragon Core" and activate "Machine Duplication" to Special Summon two "Cyber Dragons" from your Deck, due to its name becoming "Cyber Dragon" on the field, then activate "Polymerization" or "Power Bond" to Fusion Summon this card.
    • This combo can go from a one-turn Summon to an OTK by using "Limiter Removal" after Summoning "Cyber End Dragon".

Traditional Format

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