- This card can be Xyz Summoned (via "Cyber Dragon Nova") in "Galaxy", "Deskbot" and "Dinomist" Decks.
- In a "Raidraptor" Deck, "Rank-Up-Magic Soul Shave Force" can be used to Special Summon a Rank 4 "Raidraptor" monster from the Graveyard and then Xyz Summon this card.
- "Ghost Reaper & Winter Cherries" can be used to banish all copies of this card or "Cyber Dragon Nova" from the opponent's Extra Deck before they could Xyz Summon it.
- A "Superheavy Samurai" Deck can easily handle this card: they can be immune to this card's attaching effect, since they normally stay in Defense Position and also because they usually have a higher DEF than this card's ATK, being capable of defeating it in battle.
- This card can be Tributed for the Special Summon of "Lava Golem", "Santa Claws" or a "Kaiju" monster.
- This card can be baited to negate an effect, then "Ghost Ogre & Snow Rabbit" can be used to destroy it. Despite the first card will still be negated and destroyed, at least this card will be gone, since it won't be able to negate the effect of "Snow Rabbit".
- (Traditional Format) "Ghost Ogre & Snow Rabbit" can also be activated when your opponent activates the effect of "Tellarknight Ptolemaeus", so that it will be destroyed before it could Xyz Summon "Cyber Dragon Nova".
- Since this card's negation effect can only be activated once per turn, this monster's effect can be "baited" with something such as "Raigeki" and/or "Dark Hole", then another card/effect can be used to destroy this card.
- Similarly, bait out this card with any effect that would cause it to leave the field, then activate "Solemn Strike" or "Divine Wrath" in response to get rid of this card.
- In a "Heraldic Beast" Deck, Xyz Summon "Number 8: Heraldic King Genom-Heritage" to copy the effect of "Cyber Dragon Infinity", and attach it to "Genom-Heritage" as an Xyz Material. Note that this strategy requires baiting the negation effect of "Infinity" first.
- The effect of "Tellarknight Ptolemaeus" can be used to Xyz Summon "Cyber Dragon Nova".
Japanese name Primary type Secondary type ATK DEF Constellar Antares セイクリッド・アンタレス Effect Monster 2400 900 Cyber Barrier Dragon サイバー・バリア・ドラゴン Effect Monster 800 2800 Powered Inzektron 甲化鎧骨格 Synchro Monster
2500 1600 UFOroid ユーフォロイド Effect Monster 1200 1200 VW-Tiger Catapult ＶＷ－タイガー・カタパルト Fusion Monster
2000 2100 XY-Dragon Cannon ＸＹ－ドラゴン・キャノン Fusion Monster
2200 1900 XZ-Tank Cannon ＸＺ－キャタピラー・キャノン Fusion Monster
2400 2100 YZ-Tank Dragon ＹＺ－キャタピラー・ドラゴン Fusion Monster