By controlling this card alongside with a Tuner monster and "Imperial Iron Wall", while "Quillbolt Hedgehog" is in the Graveyard, it is possible to perform an OTK, by continuously Special Summoning it by its own effect and Tributing it for this card's effect, while "Iron Wall" prevent it from being banished.
Alternatively, by controlling a Tuner monster and having 2 "Quillbot Hedgehogs" on the Graveyard, Special Summon them and Xyz Summon a Rank 2 Monster. Tribute that Xyz monster and repeat this until all Rank 2 Xyz monster have been Tributed, dealing at least 6000 damage, then, Special Summon them again and Tribute them, the Tuner and this card for more 2000 damage.
With 1 "Spear Cretin" in your Graveyard, one Set or flipped face-up on the field and a card like "All-Out Attacks" active, Tribute for this card's effect the "Spear Cretin", letting you revive in face-down Defense Position the other one, which is flipped face-up by "All-Out Attacks", and repeat until victory.
Activate "Fusion Gate" and "Chain Material", then Summon this card. Using "Chain Material" and "Fusion Gate", Fusion Summon "Elemental HERO Electrum". "Elemental HERO Electrum" returns its banished Fusion Material Monsters to the Deck. Tribute it for this card's effect, then use "Fusion Gate" and "Chain Material" to Summon another. Since the first "Electrum" was banished by "Dimensional Fissure" or "Macro Cosmos", it is returned to your Extra Deck, along with the Fusion Materials, when the second is Summoned. Repeat until victory.
With "Imperial Iron Wall" and "Card of Safe Return" active, this card on the field and "Plaguespreader Zombie" in the Graveyard, activate the effect of "Plaguespreader Zombie", return 1 card from your hand to the top of your Deck and Special Summon it. "Card of Safe Return" causes you to Draw the card you just returned to your deck. Tribute "Zombie" for this card's effect, while "Iron Wall" prevents it from being banished. Repeat until victory.
When your LP are equal to or more than your opponent's, use "Ultimate Offering" to Summon "Black Ptera" and this card, then Tribute "Black Ptera". "Black Ptera" returns to your hand as it was sent to the Graveyard, but not by battle. Summon again with "Ultimate Offering" and repeat until victory. If your Life Points are less than 500 points more than your opponent's, Tribute this card at the end of this loop for victory.