This card can be used at the beginning of your turn to destroy all monsters on your opponent's field, and then use "Polymerization" to Summon "Blue-Eyes Ultimate Dragon". Once done, your "Blue-Eyes Ultimate" can attack because it is not restrained by "Burst Stream of Destruction".
"Neutron Blast" makes it possible possible to OTK with this strategy since your opponent will not be able to respond to any attack from "Ultimate Dragon".
"Destiny HERO - Diamond Dude" can activate this effect without "Blue-Eyes White Dragon" on the field and still be able to attack afterward.
This card is outstanding to a "Blue-Eyes" Deck. It destroys all of your opponent's monsters in one attack, that doesn't count toward your 1 attack every Battle Phase. As long as there are other monsters on your field that aren't "Blue-Eyes White Dragon", your opponent can still be attacked directly with your strongest monsters to win the Duel.
Use this card right after Summoning a "Blue-Eyes White Dragon" with "Paladin of White Dragon", as the former can't attack anyway.
This card can be used, then use "Hero Mask" to change the name of "Blue-Eyes", meaning it can attack, as it won't be "Blue-Eyes White Dragon" anymore.
A good combo is to Special Summon "Red-Eyes Darkness Metal Dragon", use its effect to Special Summon "Blue-Eyes White Dragon", use this card, and then have "Red-Eyes" attack directly for 2800 damage.
Just beware with "Starlight Road" if your opponent has 2 or more monsters. It would be wise if "Trap Stun" is used to ensure your safety.
A better combo is to Summon a Level 1 Tuner monster such as "Maiden with Eyes of Blue", then after "Blue-Eyes White Dragon" is Summoned, activate "Burst Stream of Destruction". This clears the field and leaves the opponent exposed for high damage. Then "Azure-Eyes Silver Dragon" can be Synchro Summoned and attack directly. Not only will this do massive damage but all of your Dragon-Type monsters are also protected from any countermeasures your opponent might have. And just to sweeten the deal the very Blue-Eyes used for the Synchro Summon can be Summoned on your next Standby Phase, making the Tuner the only monster truly sacrificed for the combo.
While this card is searchable in a "Blue-Eyes" Deck, it is better to use "Raigeki" in place of this card since you are likely to be only running one copy of this card anyway, and "Raigeki" has none of the restrictions that this card has.