- In episode 16, Akiza Izinski uses this card during her Ground Duel against Gill Randsborg. She uses this card to Special Summon "Copy Plant" from her hand.
- In episode 23, Akiza uses this card during her Ground Duel against Yusei Fudo. She uses this card to Special Summon "Dark Verger" from her hand. In the next episode, two copies of this card can be seen when "Card Defense" fully resolved.
- In episode 60, this card was shown in Akiza's hand during her Ground Duel against Misty Tredwell. In the next episode, Akiza was forced to send this card from her hand to the Graveyard via the first effect of "Dragon Queen of Tragic Endings". This card is later seen in Akiza's Graveyard when she activates "Shining Rebirth" to revive "Black Rose Dragon".
Despite Scripted Duels being based off the anime, "Seed of Deception" is a Quick-play Spell Card.