Camula appears in Part 3 as the last Shadow Rider, teaming up with a brainwashed Zane Truesdale. If Zane is the player's partner, Camula does not appear and they face Kagemaru immediatly after defeating Amnael.
After beating her in Part 3, Camula will appear in Part 1 after 10:00 P.M. in the Obelisk Blue Girls' dorm. Defeating her 10 times will earn the player her Deck Recipe and a "Vampire Genesis" card.
If the player is partnering with a Tier 2 or Tier 3 character, during their third story event, Camula and Jesse Anderson Tag Duel against the player and their partner. If the player is teaming up with Jesse at the time, Camula teams up with Atticus Rhodes instead. If Camula is the player's partner, they duel against Jesse and Atticus.
Camula uses Zombie Decks featuring a number of "Vampire" monsters and vampire-themed cards such as "Overpowering Eye". Referencing her bios, Camula also includes "Illusion Gate" in some of her Decks even when the card is Forbidden in most in-game banlists.